Scientific Literature paper GOAL: Find a Tetrahedron Letters (ElSevier publishers) journal article that describes a synthesis that includes: a molecule with at least one chiral center (your step’s product) a reaction step that we have covered the mechanism of in Organic II (LIST) Chapters 13-21 ONLY. a “work-up” that uses chromatography to purify the product and H & C-NMR to characterize the product of that step. and published between 2009 and 2019. 1. Below the title of your project, Copy/Paste the URL of the page showing the FULL-TEXT article that you have found into your submission! 2. Summarize the article and state the importance of the project briefly. This counts towards the 400-600 word project total. 3. Draw the chiral molecule product from your reaction and label at least one of its chiral centers (R/S). Draw the enantiomer of your chiral molecule and label the corresponding chiral center R/S. DO NOT CUT/PASTE FROM THE ARTICLE – DRAW IT IN PEN, PENCIL, OR CHEMDRAW. 4. Draw the FULL, ARROW-PUSHING MECHANISM for your Chapter 13-21 reaction step of choice. DO NOT CUT/PASTE FROM THE ARTICLE – DRAW IT IN PEN, PENCIL, OR CHEMDRAW. (It can be handy to draw the mechanism down the page and verbalize the mechanism step-by-step adjacent to it.) 5. Give a verbalization of the mechanism you are going to show from the article. Do not plagiarize from the internet. Use your own words. This counts towards the 400-600 word project total. 6. Detail the spectroscopy for the product of your reaction. Show the proton and carbon NMR and label ALL the product’s H to show that you know what H-NMR peaks correspond to each hydrogen atoms on your molecule. On another drawing of your molecule, label the carbons and correspond them to the carbon peaks on the NMR. 7. Describe the chromatography method used to isolate the product. This counts towards the 400-600 word project total. 8. Finally, the CITATION! Use the format of the references used in Tetrahedron Letters journal to cite the reference of the article you chose. When you publish an article, you have to use the format of that Journal! Just like MLA and APA have their own style, so does each publisher and it must be formatted appropriately for submission or it is rejected.
